Friday, October 21, 2016

Manhattan Study Crushes Cholesterol Myth

     I decided to cut & paste this email from Alan Sears, MD, because so many of my friends and family are taking statin drugs for high cholesterol.  I have read for several years that statin drugs are much worse for you than high cholesterol could ever be, but since I am not a doctor, most of them have ignored my advice that they should look for another alternative if they are concerned about cholesterol. (Many of the articles I've read say cholesterol is important for good health so I wouldn't be trying to lower mine anyway.) Anyway, here's hoping some will read it and look into the research.
    BTW:  Did you see the news today that 2 diet drinks/ day increases your risk for diabetes?  (I have also been on a crusade to get people off diet drinks because artificial sweetener is poison!)

Doctor's House CallAl Sears
Al Sears, MD
11905 Southern Blvd.
Royal Palm Beach, FL 33411
October 21, 2016

The next time your doctor says you need to lower your LDL cholesterol so you don't have a heart attack or stroke, show him the results of the Northern Manhattan Study.
The researchers that conducted the study found that higher LDL cholesterol was linked to LOWER stroke risk.1
And another study published this year reviewed research on nearly 70,000 people. The authors of that study found NO LINK between LDL cholesterol and premature deaths in people over 60 from heart disease.2
This backs up what I've been saying for two decades! LDL isn't "bad" cholesterol — and it's not what causes heart disease or strokes. 
But despite the mounting evidence that's turning conventional medicine's cholesterol myth upside-down, don't expect your doctor to change his tune anytime soon.
If you have high cholesterol, your doctor will still likely try to put you on a statin drug. Especially if you have high LDL cholesterol.
Statins are one of the most commonly prescribed drugs in the world. They're a multibillion-dollar industry.
Nearly 30% of Americans over 40 are on one. And there's been a push to up those numbers… even though statins cause dangerous side effects like liver damage and kidney failure. They can even kill you!
The truth is that heart disease and strokes are caused by inflammation and oxidation. And we can measure for that — but not by measuring cholesterol levels.
Instead, I measure levels of the amino acid homocysteine. It's the best predictor for heart disease and stroke risk.
While most conventional doctors don't test for it — because there's no Big Pharma pill to lower it — you can and should request to have your levels tested. 
Anything above 10.4 mmol/L is abnormally high. I try to get my patients under 7. 
It's a simple blood test… and it just may save your life. 
I've seen patients who had multiple strokes with homocysteine levels as high as 26 mmol/L. In fact, I've treated more than 20 patients who had as many as five strokes. I helped them lower their homocysteine levels — and all of them are alive 10 or more years later.
So how do I help my patients lower their homocysteine levels without the help of Big Pharma?
The solution is simple... 
The best way to lower your homocysteine levels is with B vitamins. Specifically, B6, B9 (also known as folic acid or folate) and B12. 
In one study, participants were treated with B6, B9 and B12 for eight weeks. At the end of the eight weeks, their homocysteine levels were cut in half.3 Another study looked at 5,522 adults with heart disease risk factors. Researchers found that taking just these three B vitamins reduced the risk of stroke by 25% compared to a placebo.4
I recommend one more additional B vitamin — B2 (riboflavin). Here's how to boost these four B vitamins with food and supplements:
VitaminFood SourcesSupplement
B6Chicken, fish, kidney, liver, eggs, bananas, lima beans, walnuts25 mg
B9 (folic acid)Beef, lamb, pork, chicken liver, eggs, green leafy vegetables, salmon800 mcg
B12Lamb, beef, herring, mackerel, liver, oysters, poultry, clams, eggs500 mcg
B2 (riboflavin)liver, nuts, dairy, eggs, seafood and dark leafy greens25 mg
I also recommend taking choline and trimethylglycine (TMG). TMG is also known as betaine.
Studies show the more choline you have, the lower your homocysteine will be. In one study, people who took in the most choline had almost 10% lower homocysteine.5 And studies on TMG show that it can reduce homocysteine by 10% in people with normal levels. People with high levels saw a reduction of 20-40%.6
The best way to get more choline is to eat a primal diet with plenty of animal meat and eggs. You can also find smaller amounts of choline in cod, cauliflower, avocados and bananas. Good sources of betaine are beets and spinach.  
To supplement with choline, look for choline citrate. Women need at least 425 mg a day; men need 550 mg. For betaine, look for a "TMG" supplement. I recommend taking 1,000 mg a day.  
To Your Good Health,
Al Sears, MD
Al Sears, MD, CNS

1. Willey JZ, Xu Q, Boden-Albala B, Paik MC, et al. "Lipid Profile Components and Risk of Ischemic Stroke: The Northern Manhattan Study (NOMAS)." Arch Neurol. 2009;66:1400-1406. 
2. Ravnskov, U, et al. "Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review." BMJ Open. Revised 21 April 2016. 
3. Undas, A, et al. Treatment of Hyperhomocysteinemia with Folic Acid and Vitamins B12 and B6 Attenuates Thrombin Generation. Thrombosis Research. 1999 Sep 15;95(6):281-288. 
4. Saposnik, G, Ray, JG, Sheridan, P., et al. "Homocysteine-Lowering Therapy and Stroke Risk, Severity, and Disability Additional Findings From the HOPE 2 Trial." Stroke. 2009;40:1365-1372. 
5. Lee J, Jacques P, Dougherty L, Selhub J, Giovannucci E, Zeisel S, Cho E. "Are dietary choline and betaine intakes determinants of total homocysteine concentration?" Am J Clin Nutr. 2010;91(5):1303-10. 
6. Margreet R. Olthof, Trinette van Vliet, Esther Boelsma, and Petra Verhoef. "Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women." J. Nutr. 2003; vol. 133 no. 12: 4135-4138.

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